عنوان به زبان ديگر :
2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium Tetrafluoroborate as an Efficient Coupling Reagent for the Amidation and Phenylhydrazation of Carboxylic Acids at Room Temperature
پديد آورندگان :
Balalaie S. نويسنده , Mahdidoust M. نويسنده , Eshaghi-Najafabadi R. نويسنده
چكيده لاتين :
The synthesis of amides and phenylhydrazides from the reaction of corresponding carboxylic acids with primary aliphatic,
aromatic amines or phenylhydrazine in the presence of triethylamine or diisopropylethyl amine as a base using 2-(1Hbenzotriazole-
1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) proceeds smoothly under mild conditions to afford the
corresponding amides or phenylhydrazides in good to high yields in ethyl acetate at room temperature.