چكيده لاتين :
Consanguinity has been a long-standing social habit among some of Iranians . The estimation of consanguinity
ratios in different parts of Iran ranged from 30 to 85%. Th is study aimed to delineating the role of consanguinity
on cong enital .malformations in Khominishahr rural population, Isfahan, Iran .
Methods: In a case-control study, 518 malformed population (case group) and 518 normal subjects (control group)
were randomly selected from khominishahr rural population, from July to November, 2003 .
Results: The frequency ofconsanguinity of par entיs was 59.7% in case group and 31.5% in control group . This different
was statistically significant (p < 0.00 I).
Conclusion: Family history of congenital malformation may play an important role in the high rates of congenital
malformation.
