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One-Pot Synthesis of 1-Aminophosphinic Acids Using 50% Hypophosphorus Acid under Microwave Irradiation

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Dedicated to Professor Habib Firouzabadi on the occasion of his 65 birthday and also his retirement A simple and efficient method has been developed for the synthesis of ل-aminophosphinic acids from hypophosphorus acid under solvent–free conditions using microwave irradiation. ل-Aminophosphinic acids were obtained in high yield under mild conditions by reaction of hypophosphorus acid with aldehydes in the presence of amines under microwave irradiation.

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