چكيده لاتين :
The oxidative hemolysis of rat erythrocytes induced by 2,2’-azobis–(2-
amidinopropane) (AAPH) and its inhibition by rosemary essential oil was studied.
Different concentrations (0.178, 0.357, 0.534 and 0.712 ىl/ml) of the essential oil
showed no significant hemolysis compared to phosphate buffer solution. AAPH (25
mM and 50 mM) induced hemolysis in a time-dependent manner. Diff e r e n t
concentrations of the essential oil inhibited hemolysis induced by 25 mM AAPH.
However, in the presence of 50 mM of AAPH, only the two higher concentrations
(0.534 and 0.712 ىl/ml) of the essential oil inhibited hemolysis. Addition of essential
oil 2 or 3 h after incubation with AAPH had no significant effects on the time course
of cell lysis. It is concluded that, in addition to its well-established antioxidant effects,
rosemary essential oil displays cytoprotective properties.
