مرکز منطقه ای اطلاع رساني علوم و فناوري -

چكيده لاتين :

Background: Effect of seasonal changes in human reproduction has been intensively researched. Some studies acknowledge influences of seasonal variation on natural conception, while others can not confirm them. The aim ofthis study was to investigate the effectof seasonal changes on different stagesof assisted reproductive technology (ART) in Tehran. Material s and Methods: Thisstudywas carriedouton268cycleswhichwerethe fi rst intracytoplasmic sperm injection (ICST) cycle of the couples between July 2005 and March 2007. Multiple logistic regression was used to model the influence of different clinical factors on pregnancy rate and a bivariate Poisson regressionmodel was used formodeling the number of mature oocytes and obtained embryos. Results: Based on the logistic regression model, the duration of infertility, female age, number of mature oocytes, and transferred embryos were only the significant predictors. In this series, seasonal changes had no predictive value on the: pregnancy rate. Bivariate Poisson regression model showed that only the female age and duration of infertility were the factors simultaneously affecting the number of embryos and mature oocytes. Conclusion: The suspected seasonalvariabilityon the outcomeofICSI cycles hasnotbeenconfirmed. Furthermore, among different seasons, there are no significan t differences in the number of mature oocytes, obtained embryos, and transferred embryos.