چكيده لاتين :
Although chronic myelogenous leukemia in pregnancy is rare, its
management and treatment is more difficult and complicated.
Treatment of patients with chronic myelogenous leukemia includes
bone marrow transplantation, however in less than 30% of
patients the donorپfs organ would be accepted. To this end, cytotoxic
therapy is considered as an alternative therapeutic option.
This option provides satisfactory hematologic and clinical response,
while cytogenetic response is poor.
Imatinib (Gleevec) is a new drug with highly specific efficacy
in the treatment of chronic myelogenous leukemia. Prescription
of this drug during pregnancy and lactation is not a
classic approach and most physicians suggest that this drug
should be discontinued during the pregnancy.
Here we report the use of imatinib during the pregnancy in
two women with chronic myelogenous leukemia.
Iran J Med Sci 2008; 33(2): 114-116.
