چكيده لاتين :
In this paper some of the latest studies and research works conducted on siliconebased
drug delivery systems (DDS) are reviewed and some of more specific and
important novel drug delivery devices are discussed in detail. An overview on
rapidly growing developments on silicone-based drug delivery systems is provided by
presenting the necessary fundamental knowledge on silicone polymers and a literature
survey including an introductory account on some of the drugs that are diffused through
silicone polymers. The results based on vast investigations over a period of a decade
indicate that intravaginal and transdermal routes of administration of the drugs using
silicone-based DDS are more developed. It is also found that silicone polymers are
suitable candidates for the release of hormonal steroids for controlling the estrous
cycle. Finally, some commercially available silicone-based DDS are described.
