پديد آورندگان :
Rantalainen Timo نويسنده , Linnamo Vesa نويسنده , Komi Paavo V. نويسنده , Kainulainen Heikki نويسنده , Heinonen Ari نويسنده
چكيده لاتين :
Bone response to a single bout of exercise can be observed with
biochemical markers of bone formation and resorption. The
purpose of this study was to examine the response of bone biochemical
markers to a single bout of exhaustive high-impact
exercise. 15 physically active young subjects volunteered to
participate. The subjects performed continuous bilateral jumping
with the ankle plantarflexors at 65 % of maximal ground reaction
force (GRF) until exhaustion. Loading was characterized by
analyzing the GRF recorded for the duration of the exercise.
Venous blood samples were taken at baseline, immediately
after, 2h and on day 1 and day 2 after the exercise. Procollagen
type I amino terminal propeptide (P1NP, marker of bone formation)
and carboxyterminal crosslinked telopeptide (CTx, marker
of bone resorption) were analyzed from the blood samples. CTx
increased significantly (32 %, p = 0.015) two days after the
exercise and there was a tendensy towards increase seen in
P1NP (p = 0.053) one day after the exercise. A significant positive
correlation (r = 0.49 to 0.69, p . 0.038) was observed between
change in P1NP from baseline to day 1 and exercise
variables (maximal slope of acceleration, body weight (BW)
adjusted maximal GRF, BW adjusted GRF exercise intensity
and osteogenic index). Based on the two biochemical bone
turnover markers, it can be concluded that bone turnover is
increased in response to a very strenuous single bout of exhaustive
high-impact exercise.