Determination of Some Biochemical Parameters of Patients with Hepatitis B in Kirkuk City

Hepatitis B infection is a worldwide healthcare problem, especially in developing areas. The current study was to evaluate the alterations in different biochemical parameters including paraoxonase (PON), 5′-Nucleotidase (5NT), total bilirubin, direct bilirubin, indirect bilirubin, Prothrombin time (PT), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), Total serum protein (TSP), albumin (Alb), Superoxide dismutase (SOD) and ɣ-glutamyl transpeptidase (GGT) in the serum samples of the viral hepatitis patients (n=100) compared with healthy controls(n=100). This study shown that there were significant increase (p 0.05) in the TSB, D. Bilirubin, In. Bilirubin, AST, ALT, PT, GGT, 5-NT, and ALP in viral hepatitis patients compared to their respective normal controls and there were significant decrease (p 0.05) in the serum (PON, SOD) activities, TSP and albumin concentration. It can be concluded that PON, 5-NT, SOD, ALT, AST, ALP and GGT may be specific method for making a diagnosis of viral hepatitis and also in distinguishing it with other kinds of hepatitis.