The protective effect of hydroalcoholic extracts of olive and morusalba leaves on liver enzymes of male rats treated with streptozotosin

The objective of this study is to investigate the effects of Olive and Morus alba leaves extracts (ethanol hydro-alcohol60%) on some liver enzyme {Serum aspartate aminotransferase (AST), Serum alanine aminotransferase (ALT)} inexperimentally STZ induced diabetes in male rats. Fifty adult male albino rats weighting (150 -200 g) were used and dividedequally into 5 experimental groups; the first group was served as a control group. The remaining groups were injected (i.p) bystreptozotocin (STZ) at 45 mg/kg B.W to induce diabetes. The 2nd diabetic group was received as control diabetic group. Thethird diabetic group was treated with Cidophage (500 mg/kg, orally). While, the fourth and fifth diabetic groups were treatedwith Olive and Morus alba leaves extracts (500 mg/kg B.W, 600 mg/kg B.W orally) respectively. All treatment groups weregiven daily for successive 30 days. The levels of (AST and ALT) were measured at 1st day after end treatments. The rats weresacrificed at the end of 30 days of treatment. The obtained results demonstrated the use of Olive and Morus alba leaves extractsimprove of (AST and ALT) levels of diabetic rats. Hydro-alcoholic extract of Olive and Morus alba leaves could improve theliver enzymes of male rats, an induced diabetes in male rats.