Synthesis and Study the Biological Activity of Some New Isoxathiozolidines by 1,3-Dipolar Cycloaddition of Nitrones and Thioacetamide

پديد آورندگان

Saleh, Zainab A. Mohammed University of Basrah - College of Education - Department of Chemistry, Iraq , Almashal, Faeza A. University of Basrah - College of Education - Department of Chemistry, Iraq , Mutlak, Dakhel Z. University of Basrah - College of Education - Department of Chemistry, Iraq

از صفحه

1

تا صفحه

10

تعداد صفحه

10

چكيده عربي

A series of new isoxathozolidines (4-6) were synthesized by 1,3-dipolar cycloaddition reaction of different nitrones with thioacetamide under reflux condition . The yields of products following recrystallization from various solvents, and characterized by spectral methods (IR , UV , TLC , M.P), were used for identification of these compounds. The biological activety show that the compounds have antibacterial activity.

چكيده لاتين

A series of new isoxathozolidines (4-6) were synthesized by 1,3-dipolar cycloaddition reaction of different nitrones with thioacetamide under reflux condition . The yields of products following recrystallization from various solvents, and characterized by spectral methods (IR , UV , TLC , M.P), were used for identification of these compounds. The biological activety show that the compounds have antibacterial activity.

كليدواژه

Nitrones , Cycloaddition , Isoxathiozolidines , Antibacterial activity.

سال انتشار

2012

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