عنوان مقاله :
Protective effect of Silymarin against kidney injury induced by carbon tetrachloride in male rats
پديد آورندگان :
ahmed, m.a. tikrit university - college of education for pure science - department of biology, Tikrit, Iraq , tayawi, h.m. tikrit university - college of education for pure science - department of biology, Tikrit, Iraq , ibrahim, m.k. tikrit university - college of education for pure science - department of biology, Tikrit, Iraq
چكيده عربي :
لا يمكن إدراج ملخص المقال
چكيده لاتين :
The herbal drugs have a protective effect for kidney function against chemical toxicity. 24 male rats divided into 4 groups and treated as following, control group administrated orally with 1ml/kg. B.W physiological solution (0.9%), One dose Carbon Tetrachloride (CCl4) 3 ml/kg. B.W, Silymarin 150 mg/kg. B.W and Silymarin150 mg/kg. B.W with CCl4 3 ml/kg. B.W for 30 days. Oxidative stress resulted by CCl4 caused increasing in Creatinine, Urea, total protein, Albumin, malondialdehyde (MDA) levels decreasing in Glutathione (GSH) and superoxide dismutase (SOD) levels in serum and congestion, degeneration and desquamation in kidney tissue. We concluded that Silymarin showed protective effect via increasing GSH, decreasing creatinine, Urea, total protein and MDA levels in serum and protect kidney tissue in rats.
كليدواژه :
Silymarin , CCl4 , Kidney toxicity , Antioxidant
عنوان نشريه :
المجله العراقيه للعلوم البيطريه
