Evaloution of effects Levothroxin, and phenolic extracts of Convolvulus arvensis on Thyroid hormonal disorders Induced in Male Mice by Thiourea

The Convolvulus was a genus from flowering plants which belong Convolvulaceae family. Convolvulus arvensis (field bindweed) was a species of bindweed which have extracts of biological activities. Many of the reports indicated Levothyroxine drugs It which are used to treat thyroid hormone deficiency. The phenolic extract for aerial parts of C. arvensis was showed enhances effect for the regulation of Thyroid hormones disorders in male mice experimental. This study indicated that levels of Triiodothyronine (T3) and thyroxine (T4 ) thyroid hormones in serum mal mice significantly decreased (p 0.05) in a group of mice which receive orally (10 mg /kg b.w) of Thiourea for 10 day, and levels (T3), (T4 ) significantly increased (p 0.05) in a group of mice receiving orally thiourea than Levothroxin respectably. In this work there was found significantly increased levels (T3), (T4 ) (p 0.05) in a group of mice which receive orally (200 mg /kg b.w) of phenolic extracts of C. arvensis. This study indicates that phenolic extracts of Convolvulus arvensis may be given the same results . as compared with the Levothroxin that plant may have active polyphenolic compound.