دراسة مقارنة لنوعية الحياة بعد استئصال الثدي الربعي واستئصال الثدي الجذري المعدل في سرطانات الثدي القنوية الغازية ذات القطر 40 ملم او اقل

Background & Objective: Assessment of quality of life after surgical treatment in breast surgery patients, and comparing quality of life between quadrantectomy and modified radical mastectomy for invasive ductal carcinoma measuring 40 mm or less. Material& methods: The study was performed prospectively by assessment of patients with invasive ductal carcinoma measuring 40 mm or less, and who were treated in Al-Byrouni University Hospital between 9/8/2009 and 1/5/2010. The patients were divided into two groups: modified radical mastectomy with axillary dissection, and quadrantectomy with axillary dissection. All patients who did not receive adjuvant radiotherapy and chemotherapy postoperatively were excluded from the study. Quality of life was assessed at least one year after surgery by Short Form 36 (SF-36). The results were compared between the two groups. Results: We studied 86 patients with invasive ductal carcinoma measuring 40 mm or less. Modified radical mastectomy with axillary dissection was performed in 58 patients (67%), and 28 patients (33%) underwent breast conserving surgery. Quality of life assessment showed better results in the group of breast conserving surgery regarding general health, limitations of activities, physical health problems, social activities, pain, and psychologic state impact, and this difference was statistically significant (p < 0.03). Conclusion: Breast conserving surgery is better than modified radical mastectomy regarding overall quality of life after surgical treatment of invasive ductal carcinoma measuring 40 mm or less, and we recommend performing quadrantectomy when indeicated as the surgical therapy of choice in order to improve the quality of life in these patients.