التقييم الشعاعي لتاثير البلاسما الغنية بعوامل النمو في الشفاء المباشر لكسور الفك السفلي

Background & Objective: maxillofacial fractures are considered among the most injuries that contemporary human being may incur; mandibular fractures form57% of them. To study the effect of PRGFin improving the direct healing of mandibular fracture line after 6 months of surgical reduction; and to evaluate this effect radiographically by using cone beam computed tomography CBCT. Material& methods: This study was performed in the hospital of oral and maxillofacialsurgery, at the Damascus University. between 2010-2011. It's a clinical comparative study. sample consisted of12 patients; (11male, 1female), they had at least onefractureline in the mandible,Aged between 16-46 years with an average age of 27.5 year. The plasma rich ingrowth factors PRGFwas prepared according to the Anitua's method, then it was applied between the two segments of the fracture (above or below the plate), which was reduced surgically by using titanium plates.In order to evaluate the effectiveness of PRGF after 6months, radiographic bone density was measured on the panoramic view on CBCT in five sections which were adopted for the study extended from buccal to lingual aspects: 20,21,22,23,24 for both the control (a), and PRGF application(b) sites. Results:research sample consisted of 15 cases of mandibular fracture in12 patients, values of bone density averagewherearranged from high to low as follows: Sitea:20,21,22,23,24; Siteb: 20,21,24,22,23. ANOVA analysis of variance showed no statistically significant differencesin the rate of average bone density between five sections studied at sites (a,b)at level of confidence95%. Conclusions:There is no important effect for PRGF in improvement of direct healing of mandibular fractures when it applied during surgery between two segmentsof fracture line