تقويم دور الصادات في الوقاية من اخماج الجروح بعد جراحة استئصال المرارة بالطريق المفتوح في مشفى الاسد الجامعي باللاذقية

patients with cholecystolithiasis were treated at AL ASSAD hospital in LATAKIA between ( 1/5/2004 – 1/5/2006 ) in order to evaluate the benefit of prophylactic antibiotics in open cholecystectomy. We conducted a prospective randomized double blind test. Patients chosen were between 20 – 60 years old and were divided into two equal groups, each having 84 patients: Group ( a ): patients received single dose of cifotaxime. Group ( b ) : patients received single dose of placebo. Operations were done under general anesthesia, and the whole agents that may affect the infection incidence rate such as: surgical technique, surgical sutures, wounds closure were similar. Postoperatively, wound infection was found in 9 patients of the first group with rate about 10.7 %, and in 8 patients of the second group with rate about 9.5 %. Because there was no clear statistic difference between both groups we concluded that there was no benefit to giving a prophylactic antibiotics in open cholecystectomy.