STUDY OF SOME IMMUNOLOGICAL PARAMETERS IN PATIENT THAT INFUCTED WITH Streptococcus pyogenes

A streptococci has recognized as Streptococcus spp., associate with acute pharyngitis. S.pyogenes infection Has detected in the Hospital and Health Center in Tikrit city. Throatswabs sample has obtained and cultured on a sheep blood agar plate. Identification of S.pyogenes was performed by using the VITEK 2 automatic system. It detected of 50samples from children included 25 were positive for S. pyogenes infection. were aged 10-35 years old and included 30 male and 20 female. . While 25 sample Negative of S.pyogenes infection (The control group included 25 clinically healthy children without S.pyogenes infection matched for age and sex with cases pateints). No significant differenceswas reported between tonsillitis patients and healthy control in terms of Complement 4proteins (33.21 ±14.18726 , 35.57±15.56254) , C3 (268.5±14.34 , 146.06±17.83) althoughincreased complement level in patient group. The present study revealed no significantdecrease levels of C4 of tonsillitis patients with negative ASOT than those with positive.the disease duration and ASOT have significant effect on CRP and complementscomponents serum levels in patients with tonsillitis.