شماره ركورد كنفرانس :
580
عنوان مقاله :
Synthesis of biologically active compounds: N-cyclohexyl-3-oxo-2-(3-oxo-2-azaspiro[4.5] decan-2-yl)-3- arylpropanamide
عنوان به زبان ديگر :
Synthesis of biologically active compounds: N-cyclohexyl-3-oxo-2-(3-oxo-2-azaspiro[4.5] decan-2-yl)-3- arylpropanamide
پديدآورندگان :
Amirani poor Mahboobe نويسنده , Darehkordi Ali نويسنده , Anary-Abbasinejad Mohammad نويسنده , Mohammadi Marziyeh نويسنده
كليدواژه :
Gabapentin , four-center , Intermolecular Ugi , N-Cyclohexyl-3- aryl -3-oxo-2- 3-oxo-2-azaspiro 4 5 decan-2- yl propanamide , PRODUCE
عنوان كنفرانس :
سومين همايش تكنتيك هاي نوين در شيمي و پتروشيمي نانو ايران
چكيده لاتين :
An intermolecular Ugi reaction of 2-(1-(aminomethyl)cyclohexyl)acetic acid (gabapentin) with glyoxal and cyclohexyl isocyanide and tertbutyl isocyanide under mild conditions in ethanol has been developed to produce a novel class of N-cyclohexyl-3-(aryl)-3-oxo-2-(3-oxo-2-azaspiro[4.5]decan-2- yl)propanamidein good to excellent yields. This represents the first report for the intermolecular Ugi three component reactions of gabapentin, glyoxal, and an isocyanide
شماره مدرك كنفرانس :
4456290
