Global stability analysis of an HIV infection model of CD4+ T-cells with treatment

The quality of life for patients infected with human immunodeficiency virus (HIV) has been positively influenced by the use of antiretroviral therapy (ART). In this paper, a class of mathematical HIV infection model with drug therapy is proposed which describes T-cell and viral interactions, as well as, the production and activation of latently infected T-cells. Upon determining equilibrium states of the latent T-cell model, the local and global asymptotic behavior of disease-free equilibrium is examined.