Phylogenetic and Bioinformatics analysis of Interferon beta-1 Protein

Background and Purpose: Interferon beta-1b protein is used to improve MS disease and reduce the number of attacks in patients. The phylogenetic studies and bioinformatics analysis of beta-1b interferon protein are predicted in Silico with the aim of predicting its structural potential by validated databases and tools. Materials and Methods: Physiological and physicochemical properties of interferon beta-1b protein were also studied by ProtScale and ProtParam servers. The three-dimensional structure of interferon beta-1b protein was examined using the Swiss Model server and its interactions with other proteins by the STRING platform. Results: The results of Phylogenetic analysis indicated that the human beta interferon protein showed the highest affinity in terms of the aminoacid structure of Myotis daubentoni. Investigations in the silicon structure of beta-1b proteins indicate the presence of guidance links and the presence of pathway secretions. Molecular activity has cytokine activity. The results of protein network analysis showed that there is the highest interaction between interferon beta-1b protein and interferon-1 receptor protein and interferon factor-3 regulator. Conclusion: Generally, the results showed that interferon beta-1b protein is a protein with an effective but unstable regulatory role in vitro. Bioinformatics analyzes conducted on interferon beta-1b protein provides biological fields for futures research.