Synthesis of benzofuran derivatives via ionic liquids

Benzofuran exist in various natural and synthesized products. Here, some of benzofuran derivatives is prepared viaionic liquid. α-halo ketones and different 2-hydroxy aldehydes were mixed in ionic liquid as solvent at temperature. High yield of product, easy work-up and ability of ionic liquid recycling are of the most advantages of this study[1]. We synthesis benzofuran derivatives from o-hydroxyacetophenone and salicylaldehydeand ethyl bromoacetate in K2CO3 and ionic liquid [hmim] Clattemperature Also, we synthesis benzofuran derivatives from reaction of salicylaldehydes with diverse phenacyl bromide under the action of potassium carbonate in ionic liquid [hmim]Cl as solvent at temperature of 100 OC to yield substituted benzofuran derivatives..