Synthesis of some new azo compounds via coupling reaction of 2-aminotiophenes with phenolic compounds

Azo compounds refer to the chemical compounds bearing the functional group R-N=N-R′ in which R and R′ can be either aryl or alkyl group [1] and they are useful in the fields of dyes, pigment and advanced materials. But they have several other applications too as, for example, dyes for drug, food and cosmetic applications, biomedical field [2] chiral receptors, liquid crystals and new glassy materials [3]. In this work, we initially prepared the two 2-aminotiophene derivatives from the starting materials cyclopentanone (or cyclohexanone), malononitrile and sulphur viaGewald threecomponent reaction. Then, the obtained 2-aminothiophenes were reacted with some phenolic compounds under the normal azo coupling reaction conditions tosatisfactorily give the desired products in good yields. Finally, structure of the productswas confirmed by spectroscopic methods.