The preparation of dimethyl- 4-hydroxy-8-methoxy-4-hydro chromone - 2, 3- dicarboxylate in presence of ZnO under solvent free condition

The increasing use of chromones compounds for the synthesis of other required compounds and derivatives have been caused that the appropriate procedures base on green chemistry were developed.In this work, the reaction between 3- methoxysalicylaldehyde and DMAD was done on solid bed of zinc oxide in room temperature and under solvent free condition by grinding method. Dimethyl-4-hydroxy-8-methoxy-4-hydrochromone-2,3-dicarboxylate was synthesized and characterized with suitable efficiency (60%) in 1 hour. The IR and 1H-NMR spectra were compared with previous reported compounds and the results showed that these compounds have been synthesized.