Cu (II)-Van-MCM-41 as a recyclable catalyst system for synthesis and oxidation of sulfides

Symmetrical and unsymmetrical diaryl sulfides are a class of important synthetic reagents and intermediates in organic, bio-organic, heterocyclic chemistry and medicinal [1, 2].They are found in numerous drugs displaying a broad spectrum of therapeutic activities such as antidiabetes, anti-Alzheimer‘s, anti-inflammatory, anti-cancer, anti-Parkinson‘s, and anti-HIV [3].In this work we used of vanillin for immobilization onto MCM-41 silica support to preparation of safe and appropriate Schiff base ligand. The aim of the present study was to report a simple and highly efficient protocol for synthesize of symmetrical diaryl sulfides Consequently, an efficient and environmentally friendly procedure has been used for the synthesis of symmetric sulfidesin the presence of catalytic amounts of Cu (II)-Van-MCM-41. Furthermore, the catalyst could be isolated with simple filtration and reused for several times..