پديدآورندگان :
Saljooqi Asma saljooqi.a@gmail.com Department of Chemistry, Shahid Bahonar University of Kerman, Kerman, Iran; , Shamspur Tayebeh Department of Chemistry, Shahid Bahonar University of Kerman, Kerman, Iran , Mostafavi Ali Department of Chemistry, Shahid Bahonar University of Kerman, Kerman, Iran , Afzali Daryoush Department of Environment, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran
كليدواژه :
DNA biosensor , Ag , MWCNT nanocomposites , anticancer drug , differential pulse voltammetry
چكيده فارسي :
The interaction of the anticancer agent mitoxantrone with DNA was investigated using differential pulse voltammetry. A simple and sensitive label free electrochemical DNA biosensor was proposed or the rapid determination of mitoxantrone (MTX) using a DNA-immobilized carbon nanotube/Ag nanocomposites paste electrode (Ag-MWCNTE). At first, the interaction between MTX and the DNA was studied using differential pulse voltammetry (DPV).