EVALUATION OF ANTIBACTERIAL ACTIVITIES OF BERBERIS VULGARIS ASPERMA BARK EXTRACTS ON PSEUDOMONAS AERUGINOSA AND ACINETOBACTER BAUMANNIISTANDARD STRAINS

Objectives: Although synthetic drugs and chemicals may treat illnesses to some extent, they give rise to some side effects e.g. drug resistance. Suitable alternatives are herbal medicines. The aim of this study was to evaluate the antibacterial properties of chloroform and ethanol extracts of Berberis vulgaris asperma bark against Pseudomonas aeruginosa and Acinetobacter baumannii standard strains.Material and methods: In this study, extraction was done by using ethanol and chloroform solvents. The antibacterial properties were determined by tube double serial dilution method, and then minimum inhibitory concentration (MIC) was obtained. The present study showed that the examined species were susceptible to ethanol and chloroform extracts of the bark of this medicinal plant. 31.25 mg/ml and 37.5 mg/ml of the ethanol extract and 4.48 mg/ml and 6.25 mg/ml of the choloroform extract were recorded as MICs agains Pseudomonas aeruginosa and Acinetobacter baumannii standard strains respectively.Conclusion: Further studies on active ingeridents of bark ethanol and chloroform extracts of Berberis vulgaris asperma is suggested.