EVALUATION OF ANTIBACTERIAL ACTIVITIES OF BERBERIS VULGARIS ASPERMA ROOT EXTRACTS ON ACINETOBACTER BAUMANNII AND PSEUDOMONAS AEROGINOSA STANDARD STRAINS

Objectives: Although synthetic drugs and chemicals may treat illnesses to some extent, they give rise to some side effects e.g. drug resistance. Suitable alternatives are herbal medicines. The aim of this study was to evaluate the antibacterial properties of chloroform and ethanol extracts of Berberis vulgaris asperma root against Acinetobacter baumannii and Pseudomonas aeroginosa standard strains.Materials Methods: In this study, extraction was done by using ethanol and chloroform solvents. The antibacterial properties were determined by tube double serial dilution method, and then minimum inhibitory concentration (MIC) was obtained.Results Conclusion: The present study showed that the examined species were susceptible to ethanol and chloroform extracts of the root of this medicinal plant. 75 mg/ml and 62.5 mg/ml of the ethanol extract and 1.56 mg/ml and 2.34 mg/ml of the choloroform extract were recorded as MICs against Acinetobacter baumannii and Pseudomonas aeroginosa standard strains respectively. Further studies on active ingredients of root ethanol and chloroform extracts of Berberis vulgaris asperma is suggested.