شماره ركورد كنفرانس :
4226
عنوان مقاله :
Voltammetric analysis of epirubicin in biological and pharmaceutical samples using nanostructure sensor
پديدآورندگان :
Alavi-Tabari Seyed A.R. h.karimi.maleh@gmail.com Islamic Azad University , Karimi-Maleh Hassan h.karimi.maleh@gmail.com Islamic Azad University , A. Khalilzadeh Mohamad h.karimi.maleh@gmail.com Islamic Azad University , Zareyee Daryoush h.karimi.maleh@gmail.com Islamic Azad University
كليدواژه :
Epirubicin , CuO nanoparticle , Electrochemical sensor
عنوان كنفرانس :
سيزدهمين سمينار ملي سالانه الكتروشيمي ايران
چكيده فارسي :
Epirubicin (EB) is a usual and useful anticancer drug for treat breast cancer. Due to lower side effect of EB compare to doxorubicin, this drug is favoured over doxorubicin for treat of breast cancer. The presence study showed that modifying a carbon paste electrode by CuO nanoparticle and 1-butylpyridinium hexafluorophosphate as a sensitive sensor to detect EB in the presence of topotecan (TP). The square wave voltammetric data showed that the oxidation of EB is catalyzed by modified electrode at pH = 7.0. The CPE/1-BPr/CuO-NPs showed the lower limit of detection of 0.008 μM and 0.3 μM for EB and TP, respectively. The CPE/1-BPr/CuO-NPs showed good ability for EB and TP analysis in real samples.
