پديدآورندگان :
Alizadeh Nina n-alizadeh@guilan.ac.ir Department of Chemistry, Faculty of Science, University Campus 2, University of guilan, Rasht, 4144784475, Iran-Department of Chemistry, Faculty of Science, University of guilan, Rasht, 4193833697, Iran , Malakzadeh Rusta Shokufeh Department of Chemistry, Faculty of Science, University Campus 2, University of guilan, Rasht, 4144784475, Iran
كليدواژه :
, antioxidant activity , host–guest complexes , β , cyclodextrin , γ , cyclodextrin , amlodipine besylate drug
چكيده فارسي :
The host–guest interaction of the drug materials with cyclodextrins were improved solubility and properties without outbreak sensitive into body [1]. This point were investigated according in order to papers encapsulation drugs in cyclodextrins [2]. The aim of the study was to synthesize and characterization the host–guest complexes of amlodipine besylate drug with β-cyclodextrin (β-CD) and γ-cyclodextrin (γ-CD) which has antioxidating activity property. The intraction host–guest complex was characterized by Fourier transform infrared (FTIR) and Ultrraviolet-visible (UV-vis) spectroscopics. Kinetic studies of 2,2-diphenyl-1-picrylhydrazyl (DPPH˙) cyclodextrins (CDs) complexes were done.
