شماره ركورد كنفرانس :
4518
عنوان مقاله :
Computational Fluid Dynamics simulation of a single cell of shaken Microtiter plate for determination of Air/Water interface shape
Author/Authors :
Behdad Pouran Department of Chemical Engineerin - University of Tehran, Tehran , Ghassem Amoabediny Department of Chemical Engineerin - University of Tehran, Tehran , Mohammad Sadegh Saghafinia Department of Chemical end Petroleum Engineering - Sharif University of Technology, Tehran , Mahdi Pesaran Haji Abbas Department of Life Science Engineering - Faculty of New Technologies - University of Tehran
كليدواژه :
Orbital Shaking , Hydrodynamics , Microtiter plates , Computational fluid dynamics
عنوان كنفرانس :
The 7th International Chemical Engineering Congress & Exhibition (IChEC 2011
چكيده لاتين :
Shaken microtiter plates have recently attracted tremendous attraction in HTS (high-throughput
screening) experiments. Detailed engineering analysis of such systems therefore is required to
allow for precise estimation of oxygen transfer rate (OTR) followed by hydrodynamics. To
accomplish, one may need to develop computational schemes which will help determine key
engineering parameters i.e. shear stress distribution, velocity profile and interfacial area in small
scale bioreactors. CFD (computational fluid dynamics) techniques as an invaluable tool can foster
scientists understanding of crucial parameters incorporated in miniaturized bioreactors.
Consequently,Simulation efforts leads to comprehensive understanding of detailed fluid flow in
orbital shaking vessels which are then compared in two different geometries at shaking frequency
of 100 rpm.
