The application of TiO2/SWCNTs modified ionic liquid modified carbon paste electrode as sensor for determination of carbidopa and folic acid

Carbidopa is a drug given to people with Parkinson s disease in order to inhibit peripheral metabolism of levodopa. This property is significant in that it allows a greater proportion of peripheral levodopa to cross the blood–brain barrier for central nervous system effect [1]. In this research, a highly sensitive electrochemical sensor was fabricated by modification of carbon paste electrode with ionic liquid and TiO2/SWCNTs as highly sensitive sensor for determination of carbidopa in the presence of folic acid. The fabricated sensor was used for determination of carbidopa with detection limit 0.01 M. The suggested sensor was successfully used for determination of carbidopa in the presence of folic acid with good separated signals. Finally, The sensor used for determination of two compounds in drug and urine samples.