پديدآورندگان :
Ehteshamzadeh Taraneh m.ghaffari@gu.ac.ir Polymer engineering group, Faculty of technology and engineering, Golestan University, Gorgan, Iran , Ghaffari Mehdi Polymer engineering group, Faculty of technology and engineering, Golestan University, Gorgan, Iran , Kakaei Saeed NSTRI, Nuclear Fuel Cycle Research Institute, P.O. Box 11365/8486, Tehran, Iran , Khanchi Ali Reza NSTRI, Nuclear Fuel Cycle Research Institute, P.O. Box 11365/8486, Tehran, Iran
كليدواژه :
Fe3O4 , drug delivery , hydrogel , polyvinylpyrrolidone
چكيده فارسي :
Magnetic drug delivery systems can be used in cancer treatment. In this study, magnetic nanocomposite hydrogels have been developed and demonstrated to be responsive to alternating magnetic fields. Fe3O4 nanoparticles were synthesized by co-precipitation method. The synthesized nanoparticles are modified by (3-aminopropyl)triethoxysilane (APTES) and coated with polyvinylpyrrolidone (PVP). Modified nanoparticles characterized by FTIR, SEM, XRD and magnetic properties are determined by vibrating sample magnetometer (VSM). The results indicate that PVP coated iron oxide nanoparticles are promising for magnetically targeted drug delivery.
