One-pot synthesis of 2-amino-4H-chromenes catalyzed by NiFe2O4 magnetic nanoparticles

A effective and green method has been developed for the synthesis of 2-amino-4H-tetrahydrobenzo-[b]-pyrans derivatives in the presence of NiFe2O4 MNPs. The efficiency of catalyst studying in one-pot three-component condensation reaction of malononitrile, dimedone and aromatic aldehydes without solvent under microwave irradiation. Mild reaction conditions, short reaction times, simple work-up, use of an economically convenient catalyst, and excellent product yields are the advantageous features of this method.