NaY Zeolite Modified with Monoethanol Amine (MEA-NaY) as a Green and Reusable Catalyst for the One pot Three-Component Synthesis of Spirooxindole in Water

Modified zeolite (MEA_NAY) has been applied as an effective heterogeneous catalyst for one-pot synthesis of spirooxindole via reaction of various isatins with malonitrile and 1,3-cyclohexandione in water at 900C [1, 2]. The corresponding products were obtained in high yields. The catalyst was easily recycled and reused without loss of its catalytic activity (scheme 1, table 1).