Kinetic Study of the 3-hydroxytyraminium in the Presence N-hydroxy-phenylacetamide as catalyst

We study the electrocatalytic oxidation of 3-hydroxytyraminium using N-hydroxy-phenylacetamide as catalyst with cyclic voltammetry, chronoamperometry, and differential pulse voltammetry (DPV). First, the electrochemical behavior of the modified electrode was investigated in buffer solution. Then the diffusion coefficient, electrocatalytic rate constant, and electron‐transfer coefficient for 3-hydroxytyraminium oxidation were determined using electrochemical approaches. This method was also used for the determination of 3-hydroxytyraminium in a pharmaceutical preparation using the standard addition method. The homogeneous rate constants (kobs) were estimated by comparing the experimental cyclic voltammograms with the digitally simulated voltammograms based on EC mechanism.