شماره ركورد كنفرانس :
4719
عنوان مقاله :
Study of Aqueous Biphasic sSystems Composed of Biocompatible Cholinium Aminoate Ionic Liquids as Novel Extractants and Polyethylene Glycol DiMethyl Ether for Separation of Bovine Serum Albumin (BSA)
پديدآورندگان :
Jafari Parisa parisajafary14@yahoo.com Physical Chemistry Department, University of Tabriz, Tabriz, Iran; Fax: +98 413 3340191; Tel: 04133393094; E-mail: , Zafarani-Moattar Mohammad Taghi Physical Chemistry Department, University of Tabriz, Tabriz, Iran , Shekaari Hemayat Physical Chemistry Department, University of Tabriz, Tabriz, Iran
كليدواژه :
Cholinium Aminoate , Aqueous Biphasic System , PEGDME , BSA Separation , NRTL Model
عنوان كنفرانس :
بيست و يكمين كنفرانس ملي شيمي فيزيك انجمن شيمي ايران
چكيده فارسي :
Aqueous biphasic systems, ABSs, are known as interesting media for the separation and purification of proteins [1-4]. From this viewpoint, the ambition of this work is investigating ability of cholinium aminoate ([Ch][AA]) as novel, low toxic and high biodegradable ionic liquids including of cholinium glycinate, cholinium prolinate and cholinium valinate for inducing ABSs with polyethylene glycol di-methyl ether, PEGDME, and then evaluating their performances for partitioning of bovine serum albumin, BSA, as a model protein. For achieving this purpose, binodal curves and tie-lines were experimentally measured at 298.15 K for three ABSs. Two empirical equations including Merchuk equation were applied in order to represent the binodal data. Tie-line were correlated with two versions of NRTL models (i.e. e-NRTL and m-NRTL). In addition, the partition behavior of BSA was studied by measuring of partition coefficient and extraction efficiency in mentioned systems.
