پديدآورندگان :
Shetab Boushehri Vahid Department of Toxicology and Pharmacology, Faculty of Pharmacy & Nanotechnology Research Center , Shetab Boushehri Farid Department of Chemistry, Faculty of Engineering, Islamic Azad University of Saveh , M. Mojtahedi Mohammad Chemistry & Chemical Engineering Research Center of Iran, Tehran , S. Abaee Mohammad Chemistry & Chemical Engineering Research Center of Iran, Tehran , S. Parhizkar Mohammadreza Alborz Bulk Pharmaceutical Co. 5th St, Kaveh Industrial zone, Saveh
كليدواژه :
Cefixime trihydrate , Purification , Decoloration , Zeolites
چكيده لاتين :
The present article provides an improved process for the purification of Cefixime, a cephalosporin
antibiotic with an improved quality in regard to color and solubility. A novel separation and purification
process suitable for pharmaceutical and chemical industries has been developed. The process is based on the
difference in adsorption of compound and its impurities. Cefixime impurities are separated in short time by
adsorption on a solid support. The process can be suitably adopted for the purification of organic compounds
in large scale.
