Electrochemical Behavior Study of Flutamide in Aqueous Solutions

Electrochemical behavior include reduction and then oxidation of flutamide has been studied in various pHs using cyclic voltammetry and controlled-potential coulometry. The obtained results show that the electrochemical behavior of flutamide is pH dependent. The unstable intermediate compound produced by the electrochemical method is hydrolyzed in strong alkaline media and acidic media via a different mechanism. Also, it is dimerized in mild pH conditions. The products were synthesized in aqueous solutions using electro-synthesis. The synthesized products were identified by spectroscopic methods (FT-IR, NMR and MS). In addition, in this study, a simple method is described for the electrochemical synthesis of flutamide’s dimer.