Spectoscopic Study of the Interaction of Trans_Aco Base (curcuminato) Exo Zirconium IV Hydrat and Curcumin with Bovine Serum Albumin

This study was conducted to investigate the mechanism interaction of novel complex of zirconium with curcumin ligand (trans-[ZrO(curcumin)2(H2O)].H2O) with bovine serum albumin (BSA), by means of various spectroscopic techniques. The fluorescence quenching measurements revealed that the quenching mechanism was static and the binding site of .zirconium complex to BSA was singular. Uv-Vis absorption measurement showed the maximum absorption of complex increases with increasing of BSA concentration