شماره ركورد كنفرانس :
4865
عنوان مقاله :
Novel p21-Activated Kinase 4 (PAK4) and an effective in vitro inhibitor
پديدآورندگان :
salehia N na_salehi84@yahoo.com Isfahan Universit , bordbar A Isfahan Universit
كليدواژه :
Adenosine triphosphate (ATP) , Activated protein kinase(PAK) , Inhibitors
عنوان كنفرانس :
بيست و دومين كنفرانس ملي شيمي فيزيك ايران
چكيده فارسي :
PAKs have an active role in the body, which makes it a target for cancer that can control cancer. PAK is among the various types of signaling of anecognition expression and has the most relevance to tumor genes, therefore, for many people; there is an understanding of their direct or beneficial effect on disease progression. Currently, competitive inhibitors of ATP have been studied extensively. KPT-9274 has been considered as an effective drug in pancreatic cancer. It s known as EMT. It has low toxicity and has a great impact as a medicine, and so is the reference of this work.