پديدآورندگان :
Abdi saray Fariba abdisaray38@gmail.com Department of Chemistry, Payame Noor University, PO Box 19395-3697, Tehran, Iran, , Dalili Maryam Department of Chemistry, Payame Noor University, PO Box 19395-3697, Tehran, Iran , Karimi Ziba Department of Chemistry, Payame Noor University, PO Box 19395-3697, Tehran, Iran
چكيده فارسي :
Electrochemical determination of metronidazole (MET) using graphene modified ionic liquid electrode (graphene/CILE) is described by using cyclic and differential pulse voltammetries at physiological pH 6.5. An increased peak current with a shift of peak potential to less positive value was observed using graphene modified carbon ionic liquid electrode (CILE) as compared to CILE. The effect of pH, scan rate and analyte concentration has been examined. Under the optimum conditions the peak current was linear to the concentration of metronidazole in the range 2.0×10−7 to 1.7×10−5 mol.L−1 for graphene/CILE and the detection limit was found to be 1.0×10−7 mol.L−1. The method was successfully used to determine the content of MET in the pharmaceutical preparations and human serum sample.
