Electro synthesis of nanosized particles of imidazole by 2-Nitromethylene-imidazolidine and aromatic aldehydes

Nowadays electro-synthesis is used as a new green methodology for elimination of hazardous reagents, green environment applications, elimination of dangerous substances, treatment of pollutions, and atom economy. In this method, electrons act as catalysts and since electrons are clean and renewable reagents, this methodology can be used to replace toxic or dangerous oxidizing or reducing reagents [1]. In addition, size reduction of products helps to improve bioavailability, surface area or viscosity, the rate of absorption, uniform mixing and drying and also improves dissolution rate [2, 3].Organic electro-synthesis as a new facile and green method was applied for synthesis of imidazole derivatives via knoevenagel condensations of aromatic aldehydes and 2-Nitromethylene-imidazolidine in propanol and an undivided cell in the presence of sodium bromide as an electrolyte at room temperature. In this study the anion of 1-Benzoyl-3,3,3-trifluoroacetone which was produced by anion of propanol leads the knoevenagel condensation.