Lanthanum-incorporated MCM-41composite as peroxidase mimetics for glucose detection

In this study, lanthanum-containing mesoporous MCM-41 (La-MCM-41) were synthesized and were used for colorimetric detection of glucose. The synthesized composite were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM) (Fig.1). The prepared La-MCM-41 provided high intrinsic peroxidase-like activity in the presence of peroxidise 3,3′,5,5′-tetramethylbenzidine (TMB) and H2O2 for accurate determination of glucose. This process produced a blue colour in aqueous solution that directly relates to H2O2 concentration[1]. The effect of different parameters such as the content of incorporated lanthanum, pH and temperature on the peroxidase-like activity was studied. The colorimetric detection of H2O2 was led to a linear dynamic range from 50 to 1000 µM (r2 = 0.9988) for glucose in aqueous solution(Fig.2). These results are comparable (close to) or better than some previous reports.