شماره ركورد كنفرانس :
5180
عنوان مقاله :
Synthesis of spiro[indolo[2,1-b]quinazoline-6,4 -pyrazolo[4,3-c]quinolin]-12-ones
عنوان به زبان ديگر :
Synthesis of spiro[indolo[2,1-b]quinazoline-6,4 -pyrazolo[4,3-c]quinolin]-12-ones
پديدآورندگان :
Sadeghian Zahra sadeghianzahra421@yahoo.com Department of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran , Bayat Mohammad bayat_mo@yahoo.com Department of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran
كليدواژه :
Tryptanthrin , Aromatic amine , 3 , methyl , 1 , phenyl , pyrazol , 5(4H) , one , Spiro compound.
عنوان كنفرانس :
كنگره ملي شيمي و نانو شيمي از پژوهش تا فناوري
چكيده فارسي :
A highly efficient approach for the synthesis of spiro[indolo[2,1-b]quinazoline-6,4 -pyrazolo[4,3-c]quinolin]-12-ones was reported by the combination of tryptanthrin, various aromatic amines, and 3-methyl-1-phenyl-pyrazol-5(4H)-ones in CH3CN. Trichloroacetic acid (TCAA) catalyzed this reaction and desired products were obtained in good to high yields. Moreover, this protocol presented good tolerance and compatibility with a broad range of aromatic amines with variable substituents.
