پديدآورندگان :
Golestani Aylin Department of Cellular and Molecular Biology, Faculty of Basic Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran. , Qahremani Zahra Department of Cellular and Molecular Biology, Faculty of Basic Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran. , Soleymanpour Kosar Department of Cellular and Molecular Biology, Faculty of Basic Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran. , Rouhi Parya Department of Cellular and Molecular Biology, Faculty of Basic Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran. , Jafari-Sales Abolfazl Department of Microbiology, Faculty of Basic Sciences, Kazerun Branch, Islamic Azad University, Kazerun, Iran/ Infectious Diseases Research Center, Tabriz Medical Sciences, Islamic Azad University, Tabriz, Iran. , Pashazadeh Mehrdad Department of Medical Laboratory Sciences and Microbiology, Faculty of Medical Sciences, Tabriz Medical Sciences, Islamic Azad University, Tabriz, Iran.
چكيده فارسي :
Introduction: Premature rupture of membranes (PROM) is a serious perinatal problem that may be associated with bacterial infections. The aim of this study was to evaluate the prevalence of cervical infection with Mycoplasma hominis (M. hominis) in patients with PROM. Methods: This case-control study was conducted on 100 pregnant women with PROM and 50 healthy asymptomatic pregnant women (control) in Tabriz Women s Hospital. Cervical swab samples were collected and analyzed using culture and polymerase chain reaction (PCR) techniques to identify M. hominis. Data were analyzed using Statistical package for social science (SPSS) software and Chi-square statistical tests. Results: M. hominis was detected in 20% and 49% of PROM patients by culture and PCR method, and 7% and 10% of pregnant women in the control group by culture and PCR method. A statistically significant relationship was observed between age group, history of abortion, vaginal infection before pregnancy and spontaneous rupture of membranes in pregnant women with the risk of contracting M. hominis followed by PROM in pregnant women Conclusion: The results of this study showed that cervical infection with M. hominis has a significant relationship with PROM. Therefore, screening and treatment of mycoplasma infections in pregnant women can be effective in preventing PROM.
