پديدآورندگان :
Javanparast Elham Department of Chemistry, Faculty of Science, University of Guilan, P.O. Box: 19141, Rasht, Iran, , Alizadeh Nina Department of Chemistry, Faculty of Science, University of Guilan, P.O. Box: 19141, Rasht, Iran,
كليدواژه :
Fenofibrate , β , Cyclodextrin , Complexation , Spectroscopy
چكيده فارسي :
The aim of this work was to study the physicochemical characterization of fenofibrate(FNB)-ßCD binary systems was carried out by Fourier transform infrared spectroscopy (FTIR) and 1HNMR. Phase solubility analysis revealed enhancement in the solubility of fenofibrate. Phase solubility studies revealed 1:1 M complexation of fenofibrate with ßCD. The dissolution study revealed that the drug dissolution rate was improved by the presence of ßCD.
