پديدآورندگان :
Nazemian Malihe namazian@yazd.ac.ir Department of Chemistry, Yazd University, Yazd, Iran, P.O. Box 89195 -741 , Namazian Mansoor Department of Chemistry, Yazd University, Yazd, Iran, P.O. Box 89195 -741 , Noorbala Mohammad R. Noorbala Department of Chemistry, Yazd University, Yazd, Iran, P.O. Box 89195 -741
كليدواژه :
Hydroxycarbamide , zwitterion , Hydroxyurea , G4 , ab initio.
چكيده فارسي :
Hydroxycarbamide or hydroxyurea is a hydroxylated molecule of urea which has been widely used for decades to treat many neoplastic diseases. In this study, the zwitterion formation of hydroxycarbamide in the gas and solution phases is investigated. The conversion of hydroxycarbamide to its zwitterion form is as follows:
