شماره ركورد كنفرانس :
5328
عنوان مقاله :
Poly (ester-ether-urethane) networks and their interaction with human growth hormone: Conductometry
پديدآورندگان :
Sohrabi Masoumeh m.sohrabi@student.alzahra.ac.ir Department of Biotechnology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran , Pourhosseinia Pouneh S p.pourhosseini@alzahra.ac.ir Department of Biotechnology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran , Ansari Samira Ansaris@gmail.com CinnaGen Medical Biotechnology Research Center, Alborz University of Medical science, Karaj, Iran. 2-CinnaGen research and production co., Alborz, Iran
كليدواژه :
Conductivity , Human growth hormone , Interaction , Polyurethane
عنوان كنفرانس :
بيست و سومين كنفرانس شيمي فيزيك انجمن شيمي ايران
چكيده فارسي :
In this study, the interaction between human growth hormone (hGH) with a dicationic and a single-chain polymer of poly(ester-ether-urethane) was investigated by conductometry. Thermodynamic parameters of micellization were determined, such as critical micelle concentration (CMC), critical association concentration (CAC), protein saturation point (PSP), and the average degree of ionization (α) of micelles or complexes. The values of CMC for both polymers are low, indicating a good stability of supramolecular structures in aqueous solutions. A comparison of these parameters between both polymers provides a better understanding about their physicochemical behavior in interaction with the protein
