Investigating the effect of Lactobaccilus casei consumption on the biological pathways of the immune system by GEO method.

Probiotics are microbial strains that are beneficial for health. The word probiotic is derived from a Greek word that means for life .Their first advantage is that the digestive system can control diarrhea, reduce lactose sensitivity, and minimise cholesterol absorption Probiotics modulate the intestinal microbial composition and regulate the mucosal immune response through the induction of various cytokines. The aim of this study was to investigate the gene expression profile of Lactobaccilus caseiconsumers and its effect on the immune system. enriching genes and displaying their functional information and revealing the biological mechanisms guided by these genes.For this purpose, ToppGene database was used to determine the biological pathways of significant genes .Dataset No. GSE18741 was selected for this study, which contained 28 samples, in which a comparison was made between control samples or healthy individuals(8 samples) and samples or individuals consuming Lactobaccilus casei(8 samples), finally 4 significant genes It was found (Table1) that all 4 genes were highly expressed in people who consumed Lactobacillus acidophilus.