پديدآورندگان :
kazemizadeh zahra z.kazemizadeh@yahoo.com Department of Chemical Engineering, Hakim Sabzevari University, Sabzevar, Iran , Naji mohammad Urology and Nephrology Research Center, Shahid Beheshti university of medical sciences, Tehran, Iran , Mokhtari-Hosseini zahra-bigom Department of Chemical Engineering, Hakim Sabzevari University, Sabzevar, Iran , Hatamian-zarmi A. Urology and Nephrology Research Center, Shahid Beheshti university of medical sciences, Tehran, Iran , Kianirad soheil Urology and Nephrology Research Center, Shahid Beheshti university of medical sciences, Tehran, Iran , Ansari elham Department of Life Sciences Engineering, University of Tehran, Tehran, Iran
كليدواژه :
tissue engineering , polycaprolactone , collagen , scaffold , electrospinning
چكيده فارسي :
The main goal in tissue engineering is to design and create a structure similar to the natural structure of a tissue in the body of a living organism, in order to repair injuries and tissue damage. In recent years, rapid advanced in tissue engineering and regenerative medicine has created a new approach to tissue regeneration. Among the types of biomaterials used in tissue engineering, polymers offer a wide range of properties such as plasticity, mechanical properties, and good biocompatibility. In this article, the combination of polycaprolactone(PCL) and type collagen I(Col) was used to prepare a scaffold by electrospinning method. Overall, the PCL 15%/Col 17.5% scaffold with a ratio of (75-25) had a uniform fiber structure suitable for cell studies in tissue engineering.
